Disease Pathology: Wasting Energy Fighting Infection
نویسندگان
چکیده
منابع مشابه
Disease Pathology: Wasting Energy Fighting Infection
Drosophila melanogaster infected with Mycobacterium marinum suffer metabolic wasting similar to that seen in humans suffering from tuberculosis. This wasting is linked to insulin signaling and hastens host death.
متن کاملFighting infection fly-style.
Fighting infection fly-style" (2007). Infectious Diseases and Immunology Publications and Presentations. Paper 32.
متن کاملProtein-Energy Wasting and Mortality in Chronic Kidney Disease
Protein-energy wasting (PEW) is common in patients with chronic kidney disease (CKD) and is associated with an increased death risk from cardiovascular diseases. However, while even minor renal dysfunction is an independent predictor of adverse cardiovascular prognosis, PEW becomes clinically manifest at an advanced stage, early before or during the dialytic stage. Mechanisms causing loss of mu...
متن کاملA balancing act: protein-energy wasting in chronic kidney disease.
PROTEIN ENERGY WASTING and its extreme form, cachexia, is common among patients with chronic kidney disease (CKD). This maladaptive metabolic state is fueled by inflammation and is characterized by anorexia, increased energy expenditure, ineffective utilization of nutrients, and augmented protein catabolism leading to loss of lean body mass. At the core of the regulation of energy balance is th...
متن کاملFighting disease with disease.
Small size inocula (101-103 cells) of cells from a syngeneic methylcholanthrene-induced fibro-sarcoma (FSA) induced tolerance when injected s.c. into C3Hf mice. Mice were unable to respond to subsequent challenge with moderate, immunogenic doses of FSA. Tolerance was demonstrated in an in vivo transfer (Winn) assay and an in vitro tumour-specific TH cell assay. Low zone tolerance was associated...
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ژورنال
عنوان ژورنال: Current Biology
سال: 2006
ISSN: 0960-9822
DOI: 10.1016/j.cub.2006.10.015